高 聪
发布时间:2008-12-23  (浏览:)
    高聪,女 1958年8月出生,籍贯河北,民盟盟员,学历本科,医学学士学位,广州医科大学神经病学教研室教授,博士研究生导师,中国免疫学会神经免疫分会全国委员,广东省医学会神经病学分会免疫学组副组长。曾获得广东省“南粤优秀教师”广州市优秀教师等称号。
学习经历
1982年毕业于中山医科大学(现中山大学),获学士学位,毕业后一直在广州医科大学附属医院工作,从事神经病学专业的临床、教学和科研工作。
工作业绩
近十余年来,从事多发性硬化、视神经脊髓炎的临床与实验系列研究,共承担、参与了省市级多个有关多发性硬化的科研课题,在SCI、国家级核心期刊发表相关论文20多篇。近年来,AQP4抗体、纳米材料、miRNA成为研究关注的焦点,课题组在与时俱进,建立了AQP4抗体检测、纳米材料介导的基因表达和基因沉默技术平台,试图为视神经脊髓炎的诊断、分型、转归及预后判断寻找新的分子标志物,为视神经脊髓炎的生物治疗提供新的有效手段。
此外,一直从事青年卒中的临床研究,在国际期刊中发表了近10篇有关于青年卒中的研究论文,为我国青年卒中的临床特点提供了重要的资料。
培养条件
本课题组培养研究生的重点培养内容是:基本功必须扎实、协作精神必须强、培养科学研究兴趣;研究内容一方面在理论上冲击国际前沿科学,另一方面要注意与临床相结合,重点在于诊断标志物和预后指标的研究,神经影像学的改变亦为课题组的研究方向。
欢迎有志者加盟我们的团队。
 
近期论文(第一作者或通讯作者)
1.         Long Y, Zheng Y, Chen M, Zhang B, Gao C, Shan F, Yang N, Fan Y. Serum thyroid-stimulating hormone and anti-thyroglobulin antibody are independently associated with lesions in spinal cord in central nervous system demyelinating diseases.PLoS One. 2014 Aug 5;9(8):e100672
2.         Yang N, Zhang B, Xie L, Yin J, He Y, Yang X, Gao C.The association baseline NIH Stroke Scale score with ABO blood-subtypes in young patients with acute ischemic stroke.Atherosclerosis. 2014 Jul 11;236(1):144-149.
3.         Long Y, Zheng Y, Shan F, Chen M, Fan Y, Zhang B, Gao C, Gao Q, Yang N.Development of a cell-based assay for the detection of anti-aquaporin 1 antibodies in neuromyelitis optica spectrum disorders.J Neuroimmunol. 2014 Aug 15;273(1-2):103-10
4.         Zhang B, Yang N, Gao C.Is plasma C3 and C4 levels useful in young cerebral ischemic stroke patients? Associations with prognosis at 3 months.J Thromb Thrombolysis. 2014 Jun 18. [Epub ahead of print]
5.         Long Y, Gao C.Brain embolism secondary to cardiac myxoma in fifteen Chinese patients.ScientificWorldJournal. 2014 Mar 9;2014:718246
6.         Long Y, Zheng Y, Chen M, Zhang B, Gao C, Gao Q, Yin JR, Pu S, Xie C.Antineutrophil cytoplasmic antibodies in patients with idiopathic inflammatory-demyelinating diseases.Neuroimmunomodulation. 2014;21(6):297-303.
7.         Long Y, Chen M, Zhang B, Gao C, Zheng Y, Xie L, Gao Q, Yin J. Brain gadolinium enhancement along the ventricular and leptomeningeal regions in patients with aquaporin-4 antibodies in cerebral spinal fluid. J Neuroimmunol. 2014 Apr 15;269(1-2):62-7.
8.         long Y, He Y, Zheng Y, Chen M, Zhang B, Gao C. Serum anticardiolipin antibodies in patients with neuromyelitis optica spectrum disorder.J Neurol. 2013 Dec;260(12):3150-7.
9.         Gao C, Huang L, Long Y, Zheng J, Yang J, Pu S, Xie L.Y-39983, a selective Rho-kinase inhibitor, attenuates experimental autoimmune encephalomyelitis via inhibition of demyelination.Neuroimmunomodulation. 2013;20(6):334-40.
10.     Yang N, Zhang B, Gao C.The baseline NIHSS score in female and male patients and short-time outcome: a study in young ischemic stroke.J Thromb Thrombolysis. 2014 May;37(4):565-70.
11.     Long Y, Gao C, Qiu W, Hu X, Peng F, Lu Z.Antibodies target microvessels in neuromyelitis optica and multiple sclerosis patients. Neurol Res. 2013 Nov;35(9):922-9.
12.     Liang B, Deng JJ, Yuan F, Yang N, Li W, Yin JR, Pu SX, Xie LC, Gao C, Zhang LM.Efficient gene transfection in the neurotypic cells by star-shaped polymer consisting of β-cyclodextrin core and poly(amidoamine) dendron arms.Carbohydr Polym. 2013 Apr 15;94(1):185-92.
13.     Zhang B, Gao C, Hou Q, Yin J, Xie L, Pu S, Yi Y, Gao Q.The potent different risk factors for cerebral infarction in young patients with and without type 2 diabetes: subanalysis of the Young Cerebral Infarction Study (YCIS).Atherosclerosis. 2012 Mar;221(1):215-20.
14.     Zhang B, Gao C, Hou Q, Yin J, Xie L, Pu S, Yi Y, Gao Q.Different independent susceptibility markers for first-ever cerebral infarction and myocardial infarction in young patients.J Neurol. 2012 Jul;259(7):1420-5.
15.     Zhang B, Zhang W, Li X, Pu S, Yin J, Yang N, Yi Y, Gao Q, Gao C.Admission markers predict lacunar and non-lacunar stroke in young patients.Thromb Res. 2011 Jul;128(1):14-7.
16.     Zhang B, Pu S, Zhang W, Yang N, Shen G, Yin J, Yi Y, Gao Q, Gao C.Sex differences in risk factors, etiology, and short-term outcome of cerebral infarction in young patients.Atherosclerosis. 2011 Jun;216(2):420-5.
17.     Zhang B, Gao C, Yang N, Zhang W, Song X, Yin J, Pu S, Yi Y, Gao Q.Is elevated SUA associated with a worse outcome in young Chinese patients with acute cerebral ischemic stroke?BMC Neurol. 2010 Sep 18;10:82.
18.     Gao C, Zhang B, Zhang W, Pu S, Yin J, Gao Q.Serum prealbumin (transthyretin) predict good outcome in young patients with cerebral infarction.Clin Exp Med. 2011 Mar;11(1):49-54.
19.     Zhang B, Song X, Liang B, Hou Q, Pu S, Ying JR, Gao C.The clinical study of POEMS syndrome in China.Neuro Endocrinol Lett. 2010;31(2):229-37.
20.     Zhang B, Pu S, Li B, Ying J, Song XW, Gao C.Comparison of serum apolipoprotein A-I between Chinese multiple sclerosis and other related autoimmune disease.Lipids Health Dis. 2010 Mar 29;9:34.
 
 
 
 

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