易咏红
发布时间:2012-04-28  (浏览:)

    易咏红,女, 1962年3月出生,籍贯湖南。医学博士学位,神经内科教授,博士研究生导师。1978-1983年湖南医科大学(现中南大学湘雅医学院),获学士学位;1987-1991年该校硕博连读,获博士学位。
    1991年后一直在广州医学院第二附属医院神经内科和广州医学院神经科学研究所从事医疗、教学和科研工作,2000年起聘任为神经内科教授。对神经系统疾病有良好的诊治与科研能力,有丰富的教学经验,曾被评为广州市优秀教师。研究方向为遗传性神经系统疾病,着力于脑发育调控与遗传性智能低下的分子机制研究。主持国家自然科学基金项目4项、广东省自然科学基金重点项目1项和其它省市级攻关课题多项。在Molecular Neurobiology,Neurogenetics,Psychopharmacology等国内外核心专业期刊发表论文50余篇,参与编写《儿童精神病学》和《实用临床儿科学》专著两部。作为主要成员完成的科研成果曾获广东省科技进步二等奖2项和教育部科技进步二等奖1项。目前担任广东省抗癫痫协会副会长,中华医学会广东省神经病学分会生化学组副组长,广州市神经病学分会委员。
本课题组本着“夯实学生神经病学基本功、培养科学研究思维和方法”的目标培养学生。本课题组指导的研究生学位论文多篇被SCI收录,其中最高影响因子5.286。1人获“南粤优秀研究生”称号。
 
3年发表的主要论著*为通信作者):
(1)      Ting Liu, Rui-Ping Wan, Ling-Jia Tang, Shu-Jing Liu, Hai-Jun Li, Qi-Hua Zhao, Wei-Ping Liao, Xiao-Fang Sun, Yong-Hong Yi*, Yue-Sheng Long*. A microRNA profile in Fmr1 knockout mice reveals microRNA expression alterations with possible roles in fragile X syndrome. Molecular Neurobiology, DOI 10.1007/s12035-014-8770-1
(2)      Tao Su,Hong-Xing Fan, Tao Jiang, Wei-Yi Den, Wei-Wen Sun, Mei-Mei Gao,Sheng-Qiang Chen, Qi-Hua Zhao, Lin Xu, Yong-Hong Yi*. Early continuous inhibition of group 1 mGlu signaling partially rescues dendritic spine abnormalities in the Fmr1 knockout mouse model for fragile X syndrome. Psychopharmacology,215:291-300,2011
(3)        Yong-Hong Yi, Xun-Sha Sun, Jia-Ming Qin, Qi-Hua Zhao, Wei-Ping Liao, Yue-Sheng Long. Experimental identification of microRNA targets on the 3' untranslated region of human FMR1 gene. J Neurosci Methods, 190(1): 34-38, 2010
(4)       Yu-Liang Wang, Zhi-Yong Zeng, Xing-Wang Song, Zhuo-Fang Hao, Yi-Wu Shi, Bin Tang,Sheng-Qiang Chen , Mei-Mei Gao , Wei Di,& Yue-Sheng Long, Yong-Hong Yi*WP Liao. A novel CLN2/TPP1 mutation in a Chinese patient with late infantile neuronal ceroid lipofuscinosis. Neurogenetics,12 (1) :93-95, 2011
(5)       Zhuo Zhou, Mengmeng Cao, Yang Guo, Lili Zhao, Jingfeng Wang, Xue Jia, Jianguo Li, Conghui Wang, Gülsah Gabriel, Qinghua Xue, Yonghong Yi, Sheng Cui, Qi Jin, Jianwei Wang, Tao Deng*. Fragile X mental retardation protein stimulates ribonucleoprotein assembly of Influenza A virus. Nature Communications,  2014,Feb 10;5:3259
(6)       Tian, H.; Cao, Y-X; Zhang, X-S; Liao, W-P; Yi, Y-H; Lian, J.; Liu, L.; Huang, H-L; Liu, W-J; Yin, M-M; Liang, M.; Shan, G.; *Sun, F. The targeting and functions of miRNA-383 are mediated by FMRP during spermatogenesis. Cell death and disease, 4, e617; doi:10.1038/cddis. 2013
(7)       Long YS*, Deng GF, Sun XS, Yi YH, Su T, Zhao QH, Liao WP. Identification of the transcriptional promoters in the proximal regions of human microRNA genes. Mol Biol Rep. 38(6): 4153-4157, 2011.
(8)       Long YS*, Qin JM, Su T, Zhao QH, Yi YH, Liao WP. Human transcription factor genes involved in neuronal development tend to have high GC content and CpG elements in the proximal promoter region. J Genet Genomics. 38(4): 157-163, 2011.
(9)       Shi YW, Yu MJ, Long YS, Qin B, He N, Meng H, Liu XR, Deng WY, Gao MM, Yi YH, Li BM, Liao WP. Mosaic SCN1A mutations in familial partial epilepsy with antecedent febrile seizures. Genes Brain Behav. 11(2): 170-176, 2012.
(10)   Deng GF, Qin JM, Sun XS, Kuang ZY, Su T, Zhao QH, Shi YW, Liu XR, Yu MJ, Yi YH, Liao WP, Long YS*. Promoter analysis of mouse Scn3a gene and regulation of the promoter activity by GC box and CpG methylation. J Mol Neurosci. 44(2): 115-121, 2011.
(11)   Shi YW, Yu MJ, Long YS, Qin B, He N, Meng H, Liu XR, Deng WY, Gao MM, Yi YH, Li BM, Liao WP. Mosaic SCN1A mutations in familial partial epilepsy with antecedent febrile seizures. Genes Brain Behav. 11(2): 170-176, 2012.

 

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